Xalatan Eye Drops (Latanoprost) Dosage and Side Effects
XALATAN is used to treat ocular hypertension (high pressure in the eye) in patients with open-angle glaucoma or ocular hypertension.
Warnings and Precautions
BEFORE you use XALATAN talk to your doctor or pharmacist if:
- You are allergic to any of the ingredients in XALATAN.
- You are using any other eye drops or taking any other medication.
- You are pregnant, think you might be pregnant or you are planning a pregnancy.
- You are breast feeding or planning to breastfeed.
- You have or have had herpes simplex keratitis (inflammation of the cornea caused by the herpes simplex virus).
- Your eyes are sensitive to light.
- You have liver or kidney problems.
- You have or have had eye inflammation (e.g. uveitis, iritis).
XALATAN contains a preservative that may be absorbed by contact lenses and stains them a brown colour. Contact lenses can be reinserted 15 minutes after applying the eye drops.
If you are using more than one type of eye drop medication, wait at least 5 minutes between each different eye drop.
XALATAN may change the colour of your eye. It may make your iris (the coloured part of your eye) more brown. This happens most commonly if your iris has mixed colours, i.e., blue-brown, grey-brown, green-brown or yellow-brown. If you use XALATAN in one eye only, colour changes in the iris may appear only in the treated eye. These changes may be permanent.
XALATAN may also cause your eye lashes to darken, appear thicker and longer than they usually do and increase in number. XALATAN might cause eye irritation due to the growth of misdirected eyelashes; tell your doctor if this happens. A very small number of people may notice their eyelids look darker after using XALATAN for some time. These changes may be more noticeable if you are only treating one eye. Eyelash changes are reversible after treatment with XALATAN is stopped. Eyelid skin darkening may be permanent.
When using XALATAN, you might feel as if there is something in your eye(s). Your eye(s) might water and become red. You may also develop a small cyst in your iris. As with other eye drops, if your vision is blurred when you first put your drops in, wait until this wears off before you drive or operate machinery. A few people using XALATAN have developed a skin rash.
A few people may experience changes in their vision, sometimes in combination with a red and sore/painful eye. These changes do not always occur right after administering the drops, and if they occur, you may find that reading and seeing fine details is more difficult. Although unlikely, if you experience any of these changes, stop using XALATAN and contact your doctor immediately.
Dizziness and headache have also been reported.
XALATAN may cause the following side effects as well.
Common Ocular Side Effects:
burning and stinging, blurred vision, red eyes, foreign body sensation, itching, increased iris pigmentation, damage of the cornea in a pinpoint pattern, dry eyes, excessive tearing, eye pain, eye lid crusting, red and swollen eyelid, eyelid discomfort/pain, photophobia (visual sensitivity to light).
Uncommon Ocular Side Effects:
discharge from the eye, diplopia (doubled vision), conjunctivitis, iritis/uveitis (inflammation of the interior of the eye), darkening of the palpebral skin (skin related to the eyelid), iris cyst (small cyst appearing in the colored part of the eye), disorder of the conjunctiva.
Common Systemic Side Effects:
upper respiratory tract infection/cold/flu, pain in muscle/joint/back, chest pain/angina pectoris, rash/allergic skin reaction.
Interactions with this medication
Studies have shown that precipitation occurs when eye drops containing thimerosal are mixed with XALATAN. If such drugs are used, they should be administered with an interval of at least 5 minutes between applications.
Only on your doctor’s advice, XALATAN may be used concomitantly with other topical ophthalmic products to further lower intraocular pressure. If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Proper Use of this medication
Usual adult dose:
One drop of XALATAN should be dropped into the affected eye(s) once daily. The best time to do this is in the evening.
Do not allow the dropper tip of the bottle to touch the eye or other surrounding structures, because this could contaminate the tip with common bacteria known to cause eye infections. Serious damage to the eye with subsequent loss of vision may result if you use eye drop solutions that have become contaminated. If you experience any type of eye condition or have surgery, immediately seek your doctor’s advice concerning the continued use of the bottle you are using.
If you forget to use your eye drops at the usual time, wait until it is time for your next dose. If you put too many drops in your eye(s), you may feel some slight irritation.
XALATAN is not recommended for use in children.
Follow these steps to help you use XALATAN properly:
- Wash your hands and sit or stand comfortably. If you wear contact lenses, remove them before using your eye drops.
- Once the bottle is opened, hold it in one hand and steady your thumb against your brow or the bridge of your nose.
- Use your index finger to gently pull down the lower eyelid of the affected eye(s) to create a pocket for the drop.
- Gently press the side of the bottle to allow only a single drop to fall into the pocket. Do not let the tip of the bottle touch your eye.
- Close your eye for 2 to 3 minutes.
- If your doctor has told you to use drops in both eyes, repeat the process for the other eye. XALATAN should be used until your doctor tells you to stop.
In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
If one dose is missed, treatment should continue with the next dose the following day.