Prilosec (Omeprazole) Dosage and Side Effects
PRILOSEC is used to treat symptoms of gastroesophageal reflux disease (GERD). PRILOSEC is also used to treat erosive esophagitis and Zollinger-Ellison syndrome (a condition in which the stomach produces too much acid). PRILOSEC may be used to prevent upper gastrointestinal bleeding in critically ill patients, and is part of the treatment for an infection of Helicobacter pylori, a type of bacteria that can cause stomach ulcers.
Warnings and Precautions
PRILOSEC is not intended for immediate symptom relief. It may take up to four days for you to feel the full benefit of this medication. You should call your doctor if your symptoms worsen or do not improve after 14 days of taking the drug.
Also, contact your physician if your symptoms return sooner than four months after you finish treatment with PRILOSEC.
You should continue to take PRILOSEC even if you feel well. Do not stop taking this drug without first talking to your doctor.
PPIs such as PRILOSEC may put you at an increased risk for fracturing your wrists, hips, or spine. This risk is greater if you take high doses of the medicine for long periods of time. Some people who take PRILOSEC for a long time also develop weakening of the stomach lining.
Before taking PRILOSEC, you should tell your doctor if you:
- Are of Asian descent
- Have ever had low levels of magnesium in your blood
- Have ever had liver disease
If you are taking the nonprescription form of PRILOSEC, tell your doctor if you have experienced any of the following symptoms:
- Heartburn that has lasted three months of longer
- Lightheadedness, sweating, or dizziness with your heartburn
- Chest or shoulder pain
- Shortness of breath or wheezing
- Pain that spreads to the arms, neck, or shoulders
- Unexplained weight loss
- Nausea or vomiting, especially if vomit is bloody
- Stomach pain
- Difficulty swallowing food or pain when you swallow
- Black or bloody stools
If you’re over age 50, you should ask your doctor about taking PRILOSEC. You may be at a greater risk for developing a severe form of diarrhea or experiencing a fracture.
Pregnancy and PRILOSEC
PRILOSEC is an FDA Pregnancy Category C drug, which means it’s not known how it will affect an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant before you take PRILOSEC. You should only use this medication during pregnancy when it is clearly needed.
PRILOSEC passes into breast milk, and the effects on a nursing infant are not known. You should talk to your doctor before breastfeeding while taking PRILOSEC.
Common Side Effects of PRILOSEC
You should tell your doctor if any of the following side effects are severe or don’t go away:
- Nausea or vomiting
Serious Side Effects of PRILOSEC
You should contact your doctor immediately or seek emergency medical help if you experience any of the following severe side effects:
- Rash, hives, or itching
- Swelling of the face, throat, tongue, lips, eyes, hands, feet, or lower legs
- Breathing or swallowing difficulties
- Extreme fatigue
- Fast, irregular, or pounding heartbeat
- Dizziness or lightheadedness
- Muscles spasms
- Uncontrollable shaking of a part of the body
- Diarrhea with watery stools
- Stomach pain
Interactions with this medication
You should tell your doctor about all prescription, non-prescription, illegal and recreational drugs; herbal remedies; and nutritional or dietary supplements you’re taking, especially:
- Certain antibiotics, such as ampicillin (Principen, Unasyn)
- Anticoagulants (often called “blood thinners”) such as warfarin (Coumadin, Jantoven), rivaroxaban (Xarelto), and apixaban (Eliquis).
- Atazanavir (Reyataz)
- Benzodiazepines such as diazepam (Valium)
- Cilostazol (Pletal)
- Clopidogrel (Plavix)
- Cyclosporine (Neoral, Sandimmune)
- Digoxin (Lanoxicaps, Lanoxin)
- Disulfiram (Antabuse)
- Diuretics (often called “water pills”)
- Iron supplements
- Ketoconazole (Nizoral)
- Methotrexate (Rheumatrex, Trexall)
- Nelfinavir (Viracept)
- Phenytoin (Dilantin)
- Saquinavir (Invirase)
- Tacrolimus (Prograf, Advagraf)
- Voriconazole (Vfend) and other prescription antifungal or anti-yeast drugs
Proper Use of this medication
The symptoms of overdose include the following:
- Nausea or vomiting
- Rapid heart beat
- Sweating profusely
- Blurred vision
- Dry mouth
If you suspect an overdose, you should contact a poison control center or emergency room immediately.
Missed Dose of PRILOSEC
If you miss a dose of PRILOSEC, take it as soon as you remember.
However, if it’s almost time for your next dose, skip the missed dose and continue on your regular dosing schedule. Don’t double up on doses to make up for a missed one.