Hyzaar (Losartan/HCTZ) Dosage and Side Effects
HYZAAR used to treat high blood pressure and lower the risk of stroke in people with high blood pressure and an enlarged heart.
Proper Use of this medication
HYZAAR comes as a tablet to take by mouth. It’s typically taken once or twice a day.
Your dose will depend on your medical condition and response to treatment.
Take HYZAAR with a full glass of water. It can be taken with or without food.
Follow the instructions on your prescription label carefully. Don’t take more or less HYZAAR than is recommended.
Symptoms of a HYZAAR overdose may include severe dizziness or fainting.
If you suspect an overdose, contact a poison control center or emergency room immediately.
You can get in touch with a poison control center.
Missed Dose of HYZAAR
If you miss a dose of HYZAAR, take it as soon as you remember.
But skip the missed dose if it’s almost time for your next scheduled dose.
Don’t take extra medicine to make up for a missed dose.
Common Side Effects of HYZAAR
Tell your doctor if any of the following side effects become severe or don’t go away:
- Stomach pain
- Back pain
- Mild tiredness
- Runny or stuffy nose
- Sore throat
- Dry cough
- Skin rash
Serious Side Effects of HYZAAR
Tell your doctor right away if you experience any of the symptoms listed in the HYZAAR Warnings section above, or any of the following serious side effects:
- Eye pain or vision problems
- Little or no urination
- Rapid weight gain
- Feeling lightheaded, or like you might pass out
- Extreme nausea
- Loss of appetite
- Increased thirst
- Extreme drowsiness
- Mood changes
- Pounding, fast, or slow heartbeat
- Pale skin
- Easy bleeding or bruising
- Yellowing of the skin or eyes
- Weak pulse
- Signs of anaphylaxis, a severe allergic reaction (may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)
Warnings and Precautions
Before taking HYZAAR, tell your doctor if you have, or have ever had:
- Kidney disease
- Problems with urination
- Liver disease
- Congestive heart failure
- High or low levels of potassium in your blood
- Bouts of dehydration
- Allergies to medicines (especially sulfa drugs or penicillin)
If you have diabetes or kidney disease, you may not be able to take HYZAAR along with any medicine that contains aliskiren, such as Amturnide, Tekturna, Tekamlo, or Valturna.
Rarely, HYZAAR can cause a condition that leads to kidney failure. Call your doctor immediately if you experience any of the following symptoms:
- Unexplained muscle pain, tenderness, or weakness (especially if accompanied by fever)
- Unusual tiredness
- Dark-colored urine
Don’t take HYZAAR if you’re currently unable to urinate.
Avoid taking potassium supplements or using salt substitutes while taking HYZAAR unless your doctor tells you otherwise.
You may have very low blood pressure while using HYZAAR. Tell your doctor if you experience persistent or severe weakness, vomiting, diarrhea, or sweating.
HYZAAR may increase your risk of dehydration. Avoid becoming overheated or being physically active in hot weather. Talk to your healthcare provider about how much water you should drink throughout the day.
Be sure to tell your doctor you take HYZAAR before having any type of surgery, including a dental procedure.
Keep taking HYZAAR even if you feel well. You may need to take this medicine for the rest of your life to control your blood pressure.
Don’t stop taking HYZAAR without first talking with your healthcare provider.
Your doctor will probably want to perform frequent tests to monitor your body’s response to HYZAAR. Keep all appointments with your doctor and laboratory.
Pregnancy and HYZAAR
HYZAAR contains a black-box warning because it may harm an unborn baby. Don’t take this medicine if you’re pregnant.
Stop using HYZAAR and call your doctor right away if you become pregnant while taking the medicine.
Use an effective form of birth control if you’re a woman of childbearing age.
It’s not known whether HYZAAR can pass into breast milk or hurt a breastfeeding baby.
Talk to your doctor if you’re considering breastfeeding.
Interactions with this medication
Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking, especially those listed in the HYZAAR Warnings section above, and any of the following:
- Any other diuretics (water pills)
- Barbiturates such as Luminal (phenobarbital)
- Insulin or oral diabetes medications
- Lithobid (lithium)
- Muscle relaxers
- Narcotic medications such as codeine, Avinza, MS Contin, Kadian, and Embeda (morphine); Duragesic (fentanyl); Hysingla (hydrocodone); Methadose (methadone); or Oxycontin (oxycodone)
- Non-steroidal anti-inflammatory drugs (NSAIDs) such as Advil and Motrin (ibuprofen); Aleve (naproxen); Celebrex (celecoxib); Indocin (indomethacin); Mobic (meloxicam) or Voltaren (diclofenac)
- Other blood pressure medications
- Questran (cholestyramine) or Colestid (colestipol)
- Rifadin and Rifater (rifampin)
- Steroids such as prednisone
HYZAAR and Other Interactions
HYZAAR may affect your thinking and reactions.
Don’t drive or perform any activity that requires alertness until you know how this medicine affects you.
HYZAAR and Alcohol
Alcohol may worsen certain side effects of HYZAAR. Avoid drinking alcohol while taking this drug.