Geodon (Ziprasidone) Dosage and Side Effects
GEODON is used to treat symptoms of schizophrenia and certain types of bipolar disorder.
Proper Use of this medication
GEODON comes as a capsule to take by mouth. It’s typically taken twice a day with food.
Your doctor might start you on a low dose of GEODON and gradually increase it.
Try to take this medicine around the same time each day.
Follow the instructions on your prescription label carefully when taking this medicine. Don’t use more or less GEODON than is prescribed.
GEODON may also be given as an injection at your doctor’s office, clinic, or hospital.
A health care professional will inject the medication into your muscle.
The dose and injection frequency will depend on your condition and response to treatment.
If you suspect an overdose, contact a poison control center or emergency room immediately.
Missed Dose of GEODON
If you miss a dose of oral GEODON, take it as soon as you remember.
However, if it’s almost time for your next dose, skip the missed dose and continue on your regular schedule.
Don’t double up on doses to make up for a missed one.
Call your doctor if you miss an injection of GEODON.
Common Side Effects of GEODON
Tell your doctor if any of the following symptoms become severe or don’t go away:
- Restlessness or anxiety
- Lack of energy
- Loss of appetite
- Muscle pain
- Stomach pain
- Runny nose
- Weight gain
Serious Side Effects of GEODON
Tell your doctor immediately if you experience any of the symptoms listed in the Warning section, as well as the following serious side effects:
- Fast, irregular, or pounding heartbeat
- Unusual movements of your face or body that you can’t control
- Rash, hives, or itching
- Blisters or peeling skin
- Muscle stiffness
- A painful erection that lasts for hours
Warnings and Precautions
GEODON includes a black-box warning highlighting the risk of death in older adults with dementia.
Some studies have shown antipsychotic medicines like GEODON can increase the risk of stroke, mini-stroke, or death in this population.
This drug isn’t approved to treat behavior problems in older adults with dementia.
Before taking GEODON, tell your doctor if you have or have ever had any of the following conditions:
- Heart failure, heart disease, or a heart attack
- An irregular heartbeat
- Long QT syndrome (a heart condition)
- A stroke or mini-stroke
- Breast cancer
- Liver disease
- Kidney disease
- Low levels of potassium or magnesium in your blood
- Trouble swallowing
- A history of suicidal thoughts
Also, be sure to tell your physician if you’ve ever used street drugs or abused prescription medications.
GEODON may make it harder for your body to cool down if it gets hot. Use caution and drink plenty of fluids if you’re exposed to hot weather or if you plan to exercise.
This medicine may increase the amount of prolactin (a hormone) in your blood. Call your doctor right away if you experience enlarged breasts, a missed menstrual period, decreased sexual ability, or nipple discharge.
You might experience high blood sugar episodes while taking this medicine, even if you don’t have diabetes. Tell your doctor if you have any of the following symptoms:
- Extreme thirst or hunger
- Frequent urination
- Blurred vision
This medicine might also cause dizziness or fainting if you get up too quickly from a lying position. To avoid this potential effect, get out of bed slowly and sit with your feet on the floor for a few minutes before standing up.
In 2014, the FDA issued a warning about a rare but serious skin reaction that’s associated with GEODON. The condition is known as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
Signs of DRESS include a fever with a rash and/or swollen lymph glands. Seek medical care immediately if you experience these symptoms.
Your health care provider might not want you to take GEODON if you’re also using other medications. Make sure you tell your doctor if you’re taking any of the following:
- Amiodarone (Cordarone, Pacerone)
- Arsenic trioxide (Trisenox)
- Disopyramide (Norpace)
- Dofetilide (Tikosyn)
- Dolasetron (Anzemet)
- Droperidol (Inapsine)
- Gatifloxacin (no longer available in the U.S.)
- Halofantrine (Halfan) (no longer available in the U.S.)
- Levomethadyl (ORLAAM) (no longer available in the U.S.)
- Mefloquine (Lariam)
- Mesoridazine (no longer available in the U.S.)
- Moxifloxacin (Avelox)
- Pentamidine (NebuPent, Pentam)
- Pimozide (Orap)
- Probucol (no longer available in the U.S.)
- Quinidine (Nuedexta)
- Sotalol (Betapace, Sorine, Sotylize)
- Sparfloxacin (no longer available in the U.S.)
- Tacrolimus (Astagraf, Prograf)
It might take a few weeks or longer before you experience the full benefits of GEODON. Don’t stop taking this medicine without first talking to your doctor.
GEODON ‘High’ and Abuse
Some people abuse GEODON to achieve a “high.”
Online accounts and anecdotal reports state that the drug can give users a feeling much like what is experienced with marijuana.
Using GEODON for this purpose can be dangerous. Never take more of the drug or a higher dose than is prescribed by your doctor.
Pregnancy and GEODON
It’s not known whether GEODON will harm an unborn baby. Tell your doctor if you’re pregnant or plan to become pregnant before taking this drug.
Taking an antipsychotic medication during the last three months of pregnancy may cause problems in newborns.
However, don’t stop taking GEODON if you become pregnant without first talking to your doctor.
It’s not known whether this medicine passes into breast milk or could harm a breastfeeding baby. To avoid any risks, don’t breastfeed while taking GEODON.
Interactions with this medication
Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking, especially those listed in the Warning section or any of the following:
- Certain antifungals such as ketoconazole (Nizoral)
- Aprepitant (Emend)
- Carbamazepine (Carbatrol, Tegretol, Teril)
- Clarithromycin (Biaxin, Prevpac)
- Cyclosporine (Gengraf, Neoral, Sandimmune)
- Delavirdine (Rescriptor)
- Diltiazem (Cardizem, Taztia, Tiazac)
- Diuretics (water pills)
- Dopamine agonists such as bromocriptine (Parlodel), cabergoline (Caberlin), levodopa (Sinemet), pergolide (Permax), and ropinirole (Requip)
- Efavirenz (Sustiva in Atripla)
- Fluoxetine (Prozac, Sarafem, Selfemra)
- Fluvoxamine (Luvox)
- HIV protease inhibitors including atazanavir (Reyataz), indinavir (Crixivan), lopinavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), and saquinavir (Invirase)
- Lovastatin (Altoprev, Advicor)
- Medications for high blood pressure
- Sertraline (Zoloft)
- Troleandomycin (TAO; no longer available in the U.S.)
- Verapamil (Calan, Covera, Verelan, Tarka)
- Zafirlukast (Accolate)
GEODON and Other Interactions
GEODON may make you drowsy. Don’t drive or operate machinery until you know how this medicine affects you.
GEODON and Alcohol
Consuming alcohol while taking GEODON may make you drowsier. Avoid alcohol while taking this medicine.
GEODON and Grapefruit
Grapefruit or grapefruit juice may interact with GEODON. Ask your doctor if it’s safe to consume grapefruit products while taking this medicine.