Cymbalta (Duloxetine) Information
Cymbalta is a prescription drug that can treat different types of psychiatric and non-psychiatric disorders, including:
- Chronic Musculoskeletal Pain
- Diabetic Peripheral Neuropathic Pain (DPNP)
- Generalized Anxiety Disorder (GAD)
- Major Depressive Disorder (MDD)
The generic name for Cymbalta is duloxetine.
Cymbalta increases the levels of serotonin and norepinephrine in the brain and peripheral nervous system. These molecules are neurotransmitters, which get their name because they pass messages back and forth between brain cells. When levels of serotonin or norepinephrine are out of balance, it worsens different medical conditions.
Cymbalta helps to correct these conditions by restoring normal levels of neurotransmitters.
Your doctor will prescribe the right dose based on the condition being treated. The dose can vary from 30 mg daily to 120 mg daily.
Cymbalta is available in 20 mg, 30 mg, and 60 mg capsules. It may be dosed once or twice daily.
Side effects are more common when starting Cymbalta. You may take it with food if it bothers your stomach. Other common side effects can include:
- Abdominal pain
- Decreased Appetite
- Dry mouth
- Weight loss
Cymbalta and all antidepressants may increase suicidal thoughts during the first few weeks of treatment, especially in adolescents and children.
Tell your doctor if you have a history of alcohol abuse or liver problems. The dose may need to be adjusted if you have a history of kidney problems.
Combined with other drugs that increase serotonin, Cymbalta increases the risk of Serotonin Syndrome, which is a rare medical emergency.
Tell your doctor if you have a history of stomach bleeds or ulcers.
Use with caution if you have a history of seizures or low blood pressure.
Cymbalta can interact with the following drugs:
- Alpha agonists
- Monoamine oxidase inhibitors
Store near room temperature 25°C (77°F) between 15-30°C (59-86°F). Keep away from places with a lot of moisture, like the bathroom or kitchen.
- If you are using Cymbalta for pain, it will begin working quickly, usually within the first week or two.
- If you are using Cymbalta for a psychiatric need, it may take 6-8 weeks to start working. Continue taking Cymbalta every day, even if you don’t notice a difference.
- Swallow the capsule whole, and do not break it open, crush it, or chew it.
How long do I need to take Cymbalta?
That depends. Some people take it for a short amount of time, and some people take it lifelong. Ask your doctor how long you will be taking it.
What should I do if I miss a dose of Cymbalta?
Take it as soon as you remember, unless it’s almost time for your next dose. Do not double up.
What are the risks of taking Cymbalta long-term?
There are no known long-term risks associated with Cymbalta.