Celebrex (Celecoxib) Information
Celebrex is given to treat many different types of pain disorders, including:
- Acute pain
- Ankylosing Spondylitis
- Familial Adenomatous Polyposis
- Juvenile rheumatoid arthritis
- Primary dysmenorrhea
- Rheumatoid arthritis
The generic name for Celebrex is celecoxib. It is a non-steroidal anti-inflammatory drug (NSAID), which reduces pain, inflammation, and fever.
Celebrex works by blocking prostaglandin production, a signal molecule used by the immune system to activate inflammation. The target of Celebrex is cyclooxygenase-2 (COX-2).
Celebrex is available as 100 mg or 200 mg capsules.
Your doctor will select the best dosage, which will vary based on what is being treated. The standard dosage starts at 200 mg by mouth once daily or 100 mg by mouth twice daily. The dose may be increased to 400 mg by mouth once daily or 200 mg by mouth twice daily.
Your doctor will lower the dose if you are taking certain medications that interact with Celebrex.
Common side effects of Celebrex may include:
- Abdominal pain
- Accidental injury
- Peripheral edema
- Upper respiratory tract infection
Most people only experience one or two side effects — if at all — while taking Celebrex. Talk to your doctor if your side effects are impacting your daily life.
Do not use Celebrex if you have a known allergy to sulfonamide drugs, aspirin, or other NSAIDs.
Tell your doctor if you have a history of cardiovascular disease involving thrombotic events, like heart attack or stroke.
If you have ever had a stomach (GI) bleed or stomach ulcers, use caution when taking Celebrex. Older patients are at a higher risk for GI bleeds.
Your doctor should regularly monitor your liver and kidney enzymes while taking this medication.
People with heart disease have a higher risk of retaining extra fluid (edema) while taking this medication.
You may need to adjust your drug regimen if you take any of the following:
- ACE inhibitors
- Angiotensin II receptor blockers
- Loop diuretics
- Sodium phosphates
Tell your doctor or pharmacist any time you start a new medication, including supplements and over-the-counter (OTC) medications.
Keep Celebrex near room temperature, 25°C (77°F). The storage temperature may be between 15-30°C (59-86°F)
- Take Celebrex with food, especially if you have a history of ulcers or other stomach problems.
- If you have hypertension (high blood pressure), you should regularly check your blood pressure while taking Celebrex. It can reduce the effectiveness of certain blood pressure medications.
- Do not take Celebrex in the late stages of pregnancy.
How long will I need to use Celebrex?
For short-term pain, it should be used for the shortest time possible. Some people may need to take it permanently for chronic pain.
Since Celebrex can increase the chances of getting stomach ulcers, how can I lower my risk?
Take Celebrex for the shortest amount of time possible, do not take other NSAIDs, do not drink alcohol, and do not smoke.
How long do the effects of Celebrex last?
Celebrex lasts between 12-24 hours.